F5 BIG-IP is an application delivery platform from F5 that integrates network traffic orchestration, load balancing, intelligent DNS, remote access policy management, etc. A denial of service vulnerability exists in the F5 BIG-IP TMM, which stems from an undisclosed request when configuring the BIG-IP ASM and DataSafe profiles on a virtual server that could cause the traffic management microkernel (TMM) to terminate. When the TMM process is restarted, traffic is interrupted and an attacker can exploit the vulnerability to cause a denial of service (DoS) on the BIG-IP system.