F5 BIG-IP is an application delivery platform from F5 that integrates network traffic orchestration, load balancing, intelligent DNS, remote access policy management, etc. A null pointer dereference vulnerability exists in the F5 BIG-IP TLS 1.3 iRule, which sources when a TLS 1.3 enabled LTM client or server SSL profile is configured on a virtual server and When calling the HTTP::reply iRule, an undisclosed request could cause TMM to terminate and an attacker could use this vulnerability to cause a denial of service on a BIG-IP system.