10 High
CVSS2
Attack Vector
NETWORK
Attack Complexity
LOW
Authentication
NONE
Confidentiality Impact
COMPLETE
Integrity Impact
COMPLETE
Availability Impact
COMPLETE
AV:N/AC:L/Au:N/C:C/I:C/A:C
10 High
CVSS3
Attack Vector
NETWORK
Attack Complexity
LOW
Privileges Required
NONE
User Interaction
NONE
Scope
CHANGED
Confidentiality Impact
HIGH
Integrity Impact
HIGH
Availability Impact
HIGH
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:C/C:H/I:H/A:H
9.2 High
AI Score
Confidence
High
0.002 Low
EPSS
Percentile
65.0%
This updated advisory is a follow-up to the original advisory titled ICSA-22-153-02 Illumina Local Run Manager that was published June 22, 2022, on the ICS webpage on cisa.gov/ics.
Successful exploitation of these vulnerabilities may allow an unauthenticated malicious actor to take control of the affected product remotely and take any action at the operating system level. An attacker could impact settings, configurations, software, or data on the affected product and interact through the affected product with the connected network…
The following devices and instruments using LRM software are affected:
Illumina In Vitro Diagnostic (IVD) devices:
Researcher Use Only (ROU) instruments:
LRM utilizes elevated privileges. An unauthenticated malicious actor can upload and execute code remotely at the operating system level, which can allow an attacker to change settings, configurations, software, or access sensitive data on the affected product. An attacker could also exploit this vulnerability to access APIs not intended for general use and interact through the network.
CVE-2022-1517 has been assigned to this vulnerability. A CVSS v3 base score of 10.0 has been calculated; the CVSS vector string is (AV:N/AC:L/PR:N/UI:N/S:C/C:H/I:H/A:H).
LRM contains a directory traversal vulnerability that can allow a malicious actor to upload outside the intended directory structure.
CVE-2022-1518 has been assigned to this vulnerability. A CVSS v3 base score of 10.0 has been calculated; the CVSS vector string is (AV:N/AC:L/PR:N/UI:N/S:C/C:H/I:H/A:H).
LRM does not restrict the types of files that can be uploaded to the affected product. A malicious actor can upload any file type, including executable code that allows for a remote code exploit.
CVE-2022-1519 has been assigned to this vulnerability. A CVSS v3 base score of 10.0 has been calculated; the CVSS vector string is (AV:N/AC:L/PR:N/UI:N/S:C/C:H/I:H/A:H).
LRM does not implement authentication or authorization by default. A malicious actor can inject, replay, modify, and/or intercept sensitive data.
CVE-2022-1521 has been assigned to this vulnerability. A CVSS v3 base score of 9.1 has been calculated; the CVSS vector string is (AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:N).
LRM version 2.4 and lower does not implement TLS encryption. A malicious actor can MITM attack sensitive data in-transit, including credentials.
CVE-2022-1524 has been assigned to this vulnerability. A CVSS v3 base score of 7.4 has been calculated; the CVSS vector string is (AV:N/AC:H/PR:N/UI:N/S:U/C:H/I:H/A:N).
Pentest, Ltd., (pentest.co.uk) reported these vulnerabilities to Illumina. Illumina reported these vulnerabilities to CISA.
Illumina has developed a software patch to protect against the remote exploitation of these vulnerabilities and is actively working to provide a permanent software fix for current and future instruments.
For instruments connected to the Internet, the software patch is available for download.
--------- Begin Update A: Part 1 of 1 ---------
Illumnia has released the following hashes for the Local Run Manager in its latest software patch:
Filename: LocalRunManagerSecurityPatch.msi
--------- End Update A: Part 1 of 1 ---------
For affected products not connected to the Internet, Illumina has developed other options for the installation of the software patch. Please contact Illumina Tech Support at [email protected] to obtain information about these options.
CISA recommends users take defensive measures to minimize the risk of exploitation of this vulnerability. Specifically, users should:
CISA reminds organizations to perform proper impact analysis and risk assessment prior to deploying defensive measures.
CISA also provides a section for control systems security recommended practices on the ICS webpage on cisa.gov/ics Several recommended practices are available for reading and download, including Improving Industrial Control Systems Cybersecurity with Defense-in-Depth Strategies.
Additional mitigation guidance and recommended practices are publicly available on the ICS webpage on cisa.gov/ics in the Technical Information Paper, ICS-TIP-12-146-01B–Targeted Cyber Intrusion Detection and Mitigation Strategies.
Organizations observing any suspected malicious activity should follow their established internal procedures and report their findings to CISA for tracking and correlation against other incidents.
No known public exploits specifically target these vulnerabilities.
web.nvd.nist.gov/view/vuln/detail?vulnId=CVE-2022-1517
web.nvd.nist.gov/view/vuln/detail?vulnId=CVE-2022-1518
web.nvd.nist.gov/view/vuln/detail?vulnId=CVE-2022-1519
web.nvd.nist.gov/view/vuln/detail?vulnId=CVE-2022-1521
web.nvd.nist.gov/view/vuln/detail?vulnId=CVE-2022-1524
cisa.gov/ics
cisa.gov/ics
cwe.mitre.org/data/definitions/22.html
cwe.mitre.org/data/definitions/250.html
cwe.mitre.org/data/definitions/284.html
cwe.mitre.org/data/definitions/319.html
cwe.mitre.org/data/definitions/434.html
public.govdelivery.com/accounts/USDHSCISA/subscriber/new?topic_id=USDHSCISA_138
support.illumina.com/downloads/illumina-local-run-manager-1.0.html
twitter.com/CISAgov
twitter.com/intent/tweet?text=Illumina%20Local%20Run%20Manager%20%28Update%20A%29+https://www.cisa.gov/news-events/ics-advisories/icsa-22-153-02
www.cisa.gov/uscert/ics/alerts/ICS-ALERT-10-301-01
www.cisa.gov/uscert/ics/recommended-practices
www.cisa.gov/uscert/ics/tips/ICS-TIP-12-146-01B
www.cisa.gov/uscert/sites/default/files/recommended_practices/NCCIC_ICS-CERT_Defense_in_Depth_2016_S508C.pdf
www.dhs.gov
www.dhs.gov/foia
www.dhs.gov/performance-financial-reports
www.facebook.com/CISA
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www.first.org/cvss/calculator/3.0#CVSS:3.0/AV:N/AC:H/PR:N/UI:N/S:U/C:H/I:H/A:N
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mailto:?subject=Illumina%20Local%20Run%20Manager%20%28Update%20A%29&body=www.cisa.gov/news-events/ics-advisories/icsa-22-153-02
10 High
CVSS2
Attack Vector
NETWORK
Attack Complexity
LOW
Authentication
NONE
Confidentiality Impact
COMPLETE
Integrity Impact
COMPLETE
Availability Impact
COMPLETE
AV:N/AC:L/Au:N/C:C/I:C/A:C
10 High
CVSS3
Attack Vector
NETWORK
Attack Complexity
LOW
Privileges Required
NONE
User Interaction
NONE
Scope
CHANGED
Confidentiality Impact
HIGH
Integrity Impact
HIGH
Availability Impact
HIGH
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:C/C:H/I:H/A:H
9.2 High
AI Score
Confidence
High
0.002 Low
EPSS
Percentile
65.0%